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    Effect of SMO16, a KOREAN Poly-Herbal Medicine, on Bone Mass in Ovariectomized Rat

    Seo Il-Bok, Ahn Sang-Hyun
    Kinesiology, December 2017, Vol.2(2), pp.18-22
    Korea Citation Index (NRF)
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    Title: Effect of SMO16, a KOREAN Poly-Herbal Medicine, on Bone Mass in Ovariectomized Rat
    Author: Seo Il-Bok; Ahn Sang-Hyun
    Subject: Ovariectomized Rat ; Osteoporosis ; Osteopontin ; Osteoblast ; Korean Medicine;
    Description: The objective of this study was to explore the effect of SMO16, a Korean poly-herbal medicine, on bone mass in ovariectomized (OVX) rats. The loss of bone mass is known to be associated with hormone deficiency in OVX rats. In the present study, we successfully produced the osteoporosis animal-model by dissecting the ovary. To determine the protective effect of SMO16 in OVX rat, SMO16 was administered at a dose of 2.25 g/kg in saline solution for 8 weeks after OVX. Furthermore, we evaluated the direct effect of SMO16 by using a soft X-ray system and Masson’s trichrome staining, phloxine-tartrazine staining, and immunohistochemistry in vivo. SMO16 significantly regulated the expression of proteoglycan and osteopontin. These data suggest that SMO16 exerts a protective effect against osteoporosis via the activation of proteoglycan and osteopontin that are closely associated with bone balance. Moreover, these findings suggest that SMO16 can act as a potential therapeutic agent for...
    Is part of: Kinesiology, December 2017, Vol.2(2), pp.18-22
    Identifier: 2435-0702 (ISSN)

    • Several versions

    Clinical experience and management of cervico-thoracic epidural hematoma

    Ahn, Sang-Soak, Song, Young-Jin
    Journal of Korean Neurosurgical Society, May 2010, Vol.47(5), pp.381-4 [Peer Reviewed Journal]

    • Several versions

    Comparative Effectivenesses of Pulsed Radiofrequency and Transforaminal Steroid Injection for Radicular Pain due to Disc Herniation: a Prospective Randomized Trial

    Lee, Dong Gyu, Ahn, Sang-Ho, Lee, Jungwon
    Journal of Korean medical science, August 2016, Vol.31(8), pp.1324-30 [Peer Reviewed Journal]

    • Several versions

    Feasibility study on the application of a heat-pipe type adsorption chiller

    Ahn, Sang, Kwon, Oh, Chung, Jae
    Journal of Mechanical Science and Technology, 2017, Vol.31(1), pp.421-428 [Peer Reviewed Journal]

    • Several versions

    Automatic Contrast Enhancement by Transfer Function Modification

    Bae, Tae Wuk, Ahn, Sang Ho, Altunbasak, Yucel
    ETRI journal, 2017, Vol.39(1), pp.76-86 [Peer Reviewed Journal]

    • Several versions

    Learning Curve of Percutaneous Endoscopic Lumbar Discectomy Based on the Period (Early vs. Late) and Technique (in-and-out vs. in-and-out-and-in): A Retrospective Comparative Study

    Ahn, Sang-Soak, Kim, Sang-Hyeon, Kim, Dong-Won
    Journal of Korean Neurosurgical Society, December 2015, Vol.58(6), pp.539-46 [Peer Reviewed Journal]

    • Several versions

    Hepatitis C Virus and Antiviral Drug Resistance

    Kim, Seungtaek, Han, Kwang-Hyub, Ahn, Sang Hoon
    Gut and liver, 15 November 2016, Vol.10(6), pp.890-895 [Peer Reviewed Journal]

    • Several versions

    Emerging therapies for hepatitis C

    Kim, Do Young, Ahn, Sang Hoon, Han, Kwang-Hyub
    Gut and liver, September 2014, Vol.8(5), pp.471-9 [Peer Reviewed Journal]

    • Several versions

    Safety assessment of concrete expressway bridges employing probabilistic concept

    Paik, Inyeol, Ahn, Sang-Sup, Shin, Soobong
    KSCE Journal of Civil Engineering, 2013, Vol.17(3), pp.584-593 [Peer Reviewed Journal]

    • Several versions

    Numerical investigation of a pump-jet with ring rotor using an unstructured mesh technique

    Ahn, Sang, Kwon, Oh
    Journal of Mechanical Science and Technology, 2015, Vol.29(7), pp.2897-2904 [Peer Reviewed Journal]