Comparative study of clinical outcomes between laparoscopy-assisted proximal gastrectomy (LAPG) and laparoscopy-assisted total gastrectomy (LATG) for proximal gastric cancer
Ahn, Sang-Hoon, Lee, Ju, Park, Do, Kim, Hyung-Ho
Gastric Cancer, 2013, Vol.16(3), pp.282-289
[Peer Reviewed Journal]
Title: Transforming growth factor β1 promotes migration of human periodontal ligament cells through heat shock protein 27 phosphorylation Author:Kwon, Seong-Min; Kim, Soo-A; Fujii, Shinsuke; Maeda, Hidefumi; Ahn, Sang-Gun; Yoon, Jung-Hoon Subject:Cell Movement ; Hsp27 Heat-Shock Proteins -- Metabolism ; Periodontal Ligament -- Cytology ; Transforming Growth Factor Beta1 -- Metabolism ; P38 Mitogen-Activated Protein Kinases -- Metabolism Description:
Transforming growth factor β1 (TGF-β1) regulates cellular functions including cell growth, differentiation, and migration. However, signal transduction pathways of TGF-β1 are mostly undefined in human periodontal ligament (hPDL) cells. In this study, we investigated TGF β1-induced migration focusing on heat shock protein 27 (Hsp27) activation. The cellular response to TGF-β1 by hPDL cells was measured using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and Western blot analysis. Cell migration was determined by counting migrated cells using a Chemotaxis Cell Migration Assay kit. TGF-β1 induced cell migration and increased the phosphorylation of Hsp27 and p38 mitogen-activated protein kinase (MAPK) in hPDL cells. Inhibiting p38 MAPK with SB203580 blocked TGF-β1-induced Hsp27 activation and cell migration. These findings suggest that TGF-β1-induced Hsp27 may promote the migration of hPDL cells via p38 MAPK mediated signaling. Hsp27 may be a potential target...
Is part of:
Biological & pharmaceutical bulletin, 2011, Vol.34(4), pp.486-9
Identifier:
1347-5215 (E-ISSN); 21467633 Version (PMID)
Several versions
Raster-stereographic evaluation of the effects of biomechanical foot orthoses in patients with scoliosis
Park, So Min, Ahn, Sang-Ho, Lee, A-Young, Park, In-Sik, Cho, Yun-Woo
Journal of physical therapy science, July 2016, Vol.28(7), pp.1968-71
[Peer Reviewed Journal]
The effects of biomechanical foot orthoses on the gait patterns of patients with malalignment syndrome as determined by three dimensional gait analysis
Kim, Soo-Hyun, Ahn, Sang-Ho, Jung, Gil-Su, Kim, Jin-Hyun, Cho, Yun-Woo
Journal of physical therapy science, April 2016, Vol.28(4), pp.1188-93
[Peer Reviewed Journal]
Title: In vitro and in vivo antimicrobial effect of photodynamic therapy using a highly pure chlorin e6 against Staphylococcus aureus Xen29 Author:Park, Jong-Hwan; Ahn, Mee-Young; Kim, Yong-Chul; Kim, Soo-A; Moon, Yeon-Hee; Ahn, Sang-Gun; Yoon, Jung-Hoon Subject:Photochemotherapy ; Anti-Infective Agents -- Therapeutic Use ; Photosensitizing Agents -- Therapeutic Use ; Porphyrins -- Therapeutic Use ; Skin Diseases -- Drug Therapy ; Staphylococcal Infections -- Drug Therapy Description:
Photodynamic therapy (PDT) has been recommended as an alternative therapy for various diseases including microbial infection. Recently, we developed a new method for the preparation of highly pure chlorin e(6) (Ce(6)), which has been widely used as a second-generation photosensitizer. PDT using Ce(6) was very effective for inhibition of in vitro growth of several bacterial strains. To clarify a possibility for its clinical application, in this study, we examined in vitro and in vivo antimicrobial effects of Ce(6)-mediated PDT in mice model of skin infection of Staphylococcus aureus Xen29. Inhibition zone analysis and colony forming unit (CFU) count revealed that Ce(6)-mediated PDT inhibited effectively in vitro bacterial growth. In addition, biofilm formation ability of S. aureus Xen29 was decreased by Ce(6)-mediated PDT. In vivo experiment, mice receiving Ce(6)-mediated PDT exhibited less intensity of bioluminescent signal, showing significant inhibition of bacterial growth. Furthermore,...
Is part of:
Biological & pharmaceutical bulletin, 2012, Vol.35(4), pp.509-14
Identifier:
1347-5215 (E-ISSN); 22466554 Version (PMID)
Several versions
Laparoscopic double-tract proximal gastrectomy for proximal early gastric cancer
Ahn, Sang-Hoon, Jung, Do, Son, Sang-Yong, Lee, Chang-Min, Park, Do, Kim, Hyung-Ho
Gastric Cancer, 2014, Vol.17(3), pp.562-570
[Peer Reviewed Journal]
The effects of transcutaneous neuromuscular electrical stimulation on the activation of deep lumbar stabilizing muscles of patients with lumbar degenerative kyphosis
Kim, So Yeon, Kim, Jin Hyun, Jung, Gil Su, Baek, Seung Ok, Jones, Rodney, Ahn, Sang Ho
Journal of physical therapy science, January 2016, Vol.28(2), pp.399-406
[Peer Reviewed Journal]