Title: Successful Resolution of Preretinal Haemorrhage with Intravitreal Ranibizumab Author:Noorlaila, Baharuddin; Zunaina, Embong; Raja-Azmi, Mohd-Noor Description:
We would like to report two cases of preretinal haemorrhage from two different aetiology courses of bleeding being treated with intravitreal ranibizumab and its outcome. Our first case was a 39-year-old man with a diagnosis of severe aplastic anaemia that presented with bilateral premacular haemorrhages in both eyes. His right eye vision was 6/45 and it was counting finger in the left eye. He was treated with intravitreal ranibizumab once to the right eye and twice to the left eye. Right eye showed complete resolution of premacular haemorrhage and minimal residual premacular haemorrhage in the left eye at 3 months after initial presentation. Our second case was a 32-year-old healthy teacher that presented with preretinal haemorrhage at superotemporal region extending to macular area in left eye secondary to valsalva retinopathy. Her left vision was counting finger. She was treated with single intravitreal ranibizumab to the left eye. There was significant reduction of premacular haemorrhage...
Is part of:
Case reports in ophthalmological medicine, 2016, Vol.2016, pp.4164198
2090-6722 (ISSN); 27800200 Version (PMID)
Title: CFD modelling of most probable bubble nucleation rate from binary mixture with estimation of components’ mole fraction in critical cluster Author:Hong, Ban; Keong, Lau; Shariff, Azmi Subject:Bubble nucleation rate ; Number of bubble nuclei ; CFD ; Mole fraction ; Binary mixture Description:
The employment of different mathematical models to address specifically for the bubble nucleation rates of water vapour and dissolved air molecules is essential as the physics for them to form bubble nuclei is different. The available methods to calculate bubble nucleation rate in binary mixture such as density functional theory are complicated to be coupled along with computational fluid dynamics (CFD) approach. In addition, effect of dissolved gas concentration was neglected in most study for the prediction of bubble nucleation rates. The most probable bubble nucleation rate for the water vapour and dissolved air mixture in a 2D quasi-stable flow across a cavitating nozzle in current work was estimated via the statistical mean of all possible bubble nucleation rates of the mixture (different mole fractions of water vapour and dissolved air) and the corresponding number of molecules in critical cluster. Theoretically, the bubble nucleation rate is greatly dependent on components’ mole fraction in a critical cluster. Hence, the dissolved gas concentration effect was included in current work. Besides, the possible bubble nucleation rates were predicted based on the calculated number of molecules required to form a critical cluster. The estimation of components’ mole fraction in critical cluster for water vapour and dissolved air mixture was obtained by coupling the enhanced classical nucleation theory and CFD approach. In addition, the distribution of bubble nuclei of water vapour and dissolved air mixture could be predicted via the utilisation of population balance model.
Is part of:
Continuum Mechanics and Thermodynamics, 2016, Vol.28(3), pp.655-668
0935-1175 (ISSN); 1432-0959 (E-ISSN); 10.1007/s00161-014-0398-x (DOI)