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    Jet Results in pp and Pb-Pb Collisions at ALICE

    Busch, Oliver
    Cornell University
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    Title: Jet Results in pp and Pb-Pb Collisions at ALICE
    Author: Busch, Oliver
    Subject: Nuclear Experiment
    Description: We report results on jet production in pp and Pb-Pb collisions at the LHC from the ALICE collaboration. The jet cross section in pp collisions at $\sqrt{s}$=2.76 TeV is presented, as well as the charged particle jet production cross section and measurements of the jet fragmentation and jet shape in pp collisions at $\sqrt{s}$=7 TeV. NLO pQCD calculations and simulations from MC event generators agree well with the data. Measurements of jets with a resolution parameter $R$=0.2 in Pb-Pb collisions at $\sqrt{s}_{NN}$=2.76 TeV show a strong, momentum dependent suppression in central events with respect to pp collisions. The centrality dependence of the suppression of charged particle jets relative to peripheral events is presented. The ratio of jet spectra with $R$=0.2 and $R$=0.3 is found to be similar in pp and Pb-Pb events. The analysis of the semi-inclusive distribution of charged particle jets recoiling from a high-$p_{\rm T}$ trigger hadron allows an unbiased measurement of the jet structure for larger cone radii. Comment: 4 pages, 3 figures, to appear in the proceedings of the 48th Rencontres de Moriond, La Thuile, Italy, March 9-16, 2013
    Identifier: 1306.2747 (ARXIV ID)

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    Jet Results in pp and Pb-Pb Collisions at ALICE

    Busch, Oliver
    arXiv.org, Jun 12, 2013
    © ProQuest LLC All rights reserved, Engineering Database, Publicly Available Content Database, ProQuest Engineering Collection, ProQuest Technology Collection, ProQuest SciTech Collection, Materials Science & Engineering Database, ProQuest Central (new), ProQuest Central Korea, SciTech Premium Collection, Technology Collection, ProQuest Central Essentials, ProQuest One Academic, Engineering Collection (ProQuest)
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    Title: Jet Results in pp and Pb-Pb Collisions at ALICE
    Author: Busch, Oliver
    Contributor: Busch, Oliver (pacrepositoryorg)
    Subject: Collisions ; Charged Particles ; Jets ; Dependence ; Cross Sections
    Description: We report results on jet production in pp and Pb-Pb collisions at the LHC from the ALICE collaboration. The jet cross section in pp collisions at \(\sqrt{s}\)=2.76 TeV is presented, as well as the charged particle jet production cross section and measurements of the jet fragmentation and jet shape in pp collisions at \(\sqrt{s}\)=7 TeV. NLO pQCD calculations and simulations from MC event generators agree well with the data. Measurements of jets with a resolution parameter \(R\)=0.2 in Pb-Pb collisions at \(\sqrt{s}_{NN}\)=2.76 TeV show a strong, momentum dependent suppression in central events with respect to pp collisions. The centrality dependence of the suppression of charged particle jets relative to peripheral events is presented. The ratio of jet spectra with \(R\)=0.2 and \(R\)=0.3 is found to be similar in pp and Pb-Pb events. The analysis of the semi-inclusive distribution of charged particle jets recoiling from a high-\(p_{\rm T}\) trigger hadron allows an unbiased measurement...
    Is part of: arXiv.org, Jun 12, 2013
    Identifier: 2331-8422 (E-ISSN)

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    Der Unverwertbarkeit einen Riegel vorgeschoben: Implikationen des BFH-Urteils zur Unionsrechtskonformität der Dokumentationspflicht für Verrechnungspreise

    Busch, Oliver
    Finanz-Rundschau Ertragsteuerrecht, 2013, Vol.95(20), pp.943-945
    Walter de Gruyter GmbH
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    Title: Der Unverwertbarkeit einen Riegel vorgeschoben: Implikationen des BFH-Urteils zur Unionsrechtskonformität der Dokumentationspflicht für Verrechnungspreise
    Author: Busch, Oliver
    Publisher: Verlag Dr. Otto Schmidt
    Is part of: Finanz-Rundschau Ertragsteuerrecht, 2013, Vol.95(20), pp.943-945
    Identifier: 0940-452X (ISSN); 2194-4156 (E-ISSN); 10.9785/ovs-fr-2013-943 (DOI)

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    Jets in Pb–Pb collisions at ALICE

    Busch, Oliver
    EPJ Web of Conferences, Vol.137 [Peer Reviewed Journal]

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    Polysialic acid is present in mammalian semen as a post-translational modification of the neural cell adhesion molecule NCAM and the polysialyltransferase ST8SiaII

    Simon, Peter, Bäumner, Sören, Busch, Oliver, Röhrich, René, Kaese, Miriam, Richterich, Peter, Wehrend, Axel, Müller, Karin, Gerardy-Schahn, Rita, Mühlenhoff, Martina, Geyer, Hildegard, Geyer, Rudolf, Middendorff, Ralf, Galuska
    The Journal of biological chemistry, 28 June 2013, Vol.288(26), pp.18825-33 [Peer Reviewed Journal]
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    Title: Polysialic acid is present in mammalian semen as a post-translational modification of the neural cell adhesion molecule NCAM and the polysialyltransferase ST8SiaII
    Author: Simon, Peter; Bäumner, Sören; Busch, Oliver; Röhrich, René; Kaese, Miriam; Richterich, Peter; Wehrend, Axel; Müller, Karin; Gerardy-Schahn, Rita; Mühlenhoff, Martina; Geyer, Hildegard; Geyer, Rudolf; Middendorff, Ralf; Galuska
    Subject: Cell Adhesion ; Fertilization ; Mammalian Sperm ; Ncam ; Polysaccharide ; Polysialic Acid ; Polysialyltransferase ; Post-Translational Modification ; St8siaii ; Spermatozoa ; Protein Processing, Post-Translational ; Neural Cell Adhesion Molecules -- Metabolism ; Semen -- Metabolism ; Sialic Acids -- Metabolism ; Sialyltransferases -- Metabolism
    Description: Fertilization in animals is a complex sequence of several biochemical events beginning with the insemination into the female reproductive tract and, finally, leading to embryogenesis. Studies by Kitajima and co-workers (Miyata, S., Sato, C., and Kitajima, K. (2007) Trends Glycosci. Glyc, 19, 85-98) demonstrated the presence of polysialic acid (polySia) on sea urchin sperm. Based on these results, we became interested in the potential involvement of sialic acid polymers in mammalian fertilization. Therefore, we isolated human sperm and performed analyses, including Western blotting and mild 1,2-diamino-4,5-methylenedioxybenzene-HPLC, that revealed the presence α2,8-linked polySia chains. Further analysis by a glyco-proteomics approach led to the identification of two polySia carriers. Interestingly, besides the neural cell adhesion molecule, the polysialyltransferase ST8SiaII has also been found to be a target for polysialylation. Further analysis of testis and epididymis tissue sections...
    Is part of: The Journal of biological chemistry, 28 June 2013, Vol.288(26), pp.18825-33
    Identifier: 1083-351X (E-ISSN); 23671285 Version (PMID); 10.1074/jbc.M113.451112 (DOI)

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    Where have all the graduates gone? Internal cross-state migration of graduates in Germany 1984–2004

    Busch, Oliver, Weigert, Benjamin
    The Annals of Regional Science, 2010, Vol.44(3), pp.559-572 [Peer Reviewed Journal]

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    Posthepatectomy bile leakage: how to manage

    Hoekstra, Lisette T, Van Gulik, Thomas M, Gouma, Dirk J, Busch, Oliver R
    Digestive surgery, 2012, Vol.29(1), pp.48-53 [Peer Reviewed Journal]
    MEDLINE/PubMed (U.S. National Library of Medicine)
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    Title: Posthepatectomy bile leakage: how to manage
    Author: Hoekstra, Lisette T; Van Gulik, Thomas M; Gouma, Dirk J; Busch, Oliver R
    Subject: Anastomotic Leak -- Therapy ; Hepatectomy -- Adverse Effects
    Description: Biliary leakage after liver resection continues to be reported. Management of bile leakage has changed in recent years, with nowadays non-surgical procedures as the preferred treatment. Biliary leakage and management were assessed in 381 patients who underwent liver resection between January 2005 and April 2011. The overall rate of biliary leakage after liver resection was 5.0%, with a higher incidence in patients who had undergone concomitant hepaticojejunostomy (HJ; 13.6 vs. 3.2%). Hospital stay (p = 0.047), major resections (p = 0.018), operation time (p = 0.011), and relaparotomy (p = 0.002) were risk factors for postoperative bile leakage. Multivariate analysis identified relaparotomy as an independent factor (OR 4.216, p = 0.034). Bile leakage in patients without HJ (n = 10) was managed in 6 patients by percutaneous transhepatic biliary drainage (PTD), and in 3 patients by endoscopic drainage. One patient was treated surgically. All patients with an HJ and postoperative bile leakage (n = 9) underwent PTD. The incidence of posthepatectomy biliary leakage has decreased over time, while PTD and endoscopic stenting are effective treatment modalities. PTD is the treatment of choice in bile leakage after resection combined with HJ.
    Is part of: Digestive surgery, 2012, Vol.29(1), pp.48-53
    Identifier: 1421-9883 (E-ISSN); 22441620 Version (PMID); 10.1159/000335734 (DOI)

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    Vascular occlusion or not during liver resection: the continuing story

    Hoekstra, Lisette T, Van Trigt, Jessica D, Reiniers, Megan J, Busch, Oliver R, Gouma, Dirk J, Van Gulik, Thomas M
    Digestive surgery, 2012, Vol.29(1), pp.35-42 [Peer Reviewed Journal]
    MEDLINE/PubMed (U.S. National Library of Medicine)
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    Title: Vascular occlusion or not during liver resection: the continuing story
    Author: Hoekstra, Lisette T; Van Trigt, Jessica D; Reiniers, Megan J; Busch, Oliver R; Gouma, Dirk J; Van Gulik, Thomas M
    Subject: Ischemic Preconditioning ; Blood Loss, Surgical -- Prevention & Control ; Hepatectomy -- Methods ; Liver -- Blood Supply
    Description: Vascular occlusion can be applied during liver resection to reduce blood loss. Herein, we provide an update of the current evidence concerning vascular occlusion. A systematic literature search was conducted to review the effects of liver in- and outflow occlusion techniques during liver resection, focusing on blood loss and hepatic ischemia-reperfusion injury. The Pringle maneuver (PM) is effective in controlling blood loss; however, there is no indication for routine vascular clamping during hepatic resection in uncomplicated patients. During complex resections and in patients with abnormal liver parenchyma, the intermittent PM is preferred over continuous clamping. Total hepatic vascular exclusion (THVE) is indicated only in resection of tumors involving the inferior caval vein or the caval hepatic junction. THVE can be applied with the preservation of caval vein flow. This mode of selective hepatic vascular exclusion results in less blood loss in combination with the PM. If clamping is necessary during complex resections or in abnormal liver parenchyma, intermittent PM is advised. THVE or selective hepatic vascular exclusion may be considered in tumors involving the inferior caval vein or the caval hepatic junction. There is no evidence supporting the use of ischemic preconditioning, maintenance of a low central venous pressure or of pharmacological interventions during liver resection.
    Is part of: Digestive surgery, 2012, Vol.29(1), pp.35-42
    Identifier: 1421-9883 (E-ISSN); 22441618 Version (PMID); 10.1159/000335724 (DOI)

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    Tumor manipulation during pancreatic resection for pancreatic cancer induces dissemination of tumor cells into the peritoneal cavity: a systematic review

    Steen, M Willemijn, Van Duijvenbode, Dennis C, Dijk, Frederike, Busch, Oliver R, Besselink, Marc G, Gerhards, Michael F, Festen, Sebastiaan
    HPB : the official journal of the International Hepato Pancreato Biliary Association, April 2018, Vol.20(4), pp.289-296 [Peer Reviewed Journal]
    MEDLINE/PubMed (U.S. National Library of Medicine)
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    Title: Tumor manipulation during pancreatic resection for pancreatic cancer induces dissemination of tumor cells into the peritoneal cavity: a systematic review
    Author: Steen, M Willemijn; Van Duijvenbode, Dennis C; Dijk, Frederike; Busch, Oliver R; Besselink, Marc G; Gerhards, Michael F; Festen, Sebastiaan
    Subject: Medicine;
    Description: Intraoperative tumor manipulation may induce the dissemination of occult peritoneal tumor cells (OPTC) into the peritoneal cavity. A systematic review was performed in the PubMed, Embase and Cochrane databases from inception to March 15, 2017. Eligible were studies that analyzed the presence of OPTC in peritoneal fluid, by any method, both before and after resection in adults who underwent intentionally curative pancreatic resection for histopathologically confirmed pancreatic ductal adenocarcinoma in absence of macroscopic peritoneal metastases. Four studies with 138 patients met the inclusion criteria. The pooled rate of OPTC prior to tumor manipulation was 8% (95% CI 2%-24%). The pooled detection rate of OPTC in patients in whom OPTC became detectable only after tumor manipulation was 33% (95% CI 15-58%). Only one study (28 patients) reported on survival, which was worse in patients with OPTC (median 11.1 months versus 30.3 months; p = 0.030). This systematic review suggests that tumor manipulation induces OPTC in one third of patients with pancreatic cancer. Since data on survival are lacking, future studies should determine the prognostic consequences of tumor manipulation, including the potential therapeutic effect of 'no-touch' and minimally invasive resection strategies.
    Is part of: HPB : the official journal of the International Hepato Pancreato Biliary Association, April 2018, Vol.20(4), pp.289-296
    Identifier: 1477-2574 (E-ISSN); 29366814 Version (PMID); 10.1016/j.hpb.2017.08.018 (DOI)

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    Extent of liver resection for hilar cholangiocarcinoma (Klatskin tumor): how much is enough?

    Van Gulik, Thomas M, Ruys, Anthony T, Busch, Oliver R C, Rauws, Erik A J, Gouma, Dirk J
    Digestive surgery, 2011, Vol.28(2), pp.141-7 [Peer Reviewed Journal]
    MEDLINE/PubMed (U.S. National Library of Medicine)
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    Title: Extent of liver resection for hilar cholangiocarcinoma (Klatskin tumor): how much is enough?
    Author: Van Gulik, Thomas M; Ruys, Anthony T; Busch, Oliver R C; Rauws, Erik A J; Gouma, Dirk J
    Subject: Cholangiocarcinoma -- Pathology ; Hepatectomy -- Methods ; Liver Neoplasms -- Pathology
    Description: Hilar resection in combination with extended liver resections has resulted in a higher rate of R0 resections and increased survival in patients with hilar cholangiocarcinoma (HCCA). This aggressive surgical approach is, however, associated with high rates of operative morbidity and mortality, largely due to postresectional liver failure. We previously reported a series after resection of HCCA in which R0 resection rate was 59% with a mortality rate of 10%. In this study, we assessed mortality of extended liver resections after optimizing liver functional reserve and application of parenchyma-sparing techniques. From 2008 until June 2010, 41 consecutive patients underwent resection on the suspicion of HCCA. Preoperative workup included staging laparoscopy, preoperative biliary drainage, assessment of volume/function of future remnant liver and radiation therapy to prevent seeding metastases. Modified right and left extended hemihepatectomies were performed preserving parts of segments 4 and 8, respectively, while pursuing complete excision of the tumor. Outcomes of resection were evaluated. The majority of resections (78%) were performed for Bismuth type III-IV tumors. Preoperative biliary drainage was undertaken in 37 (90%) patients. Hilar resection in combination with liver resection was performed in 35 (85%) patients. Of these resections, 61% were modified extended resections including central liver resections. The R0 resection rate was 92%. Postoperative morbidity and mortality rates were 54 and 7%, respectively. Strategies to optimize liver function and to reduce removal of functional liver parenchyma were associated with a decrease in mortality (7%) while undertaking extended resection for HCCA with an R0 resection rate of 92%.
    Is part of: Digestive surgery, 2011, Vol.28(2), pp.141-7
    Identifier: 1421-9883 (E-ISSN); 21540600 Version (PMID); 10.1159/000323825 (DOI)