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    Abiotic Stress: Molecular Genetics and Genomics

    Mukesh Jain Rohini Garg Rajeev K Varshney
    Frontiers Media SA
    2014
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    Title: Abiotic Stress: Molecular Genetics and Genomics
    Author: Mukesh Jain Rohini Garg Rajeev K Varshney
    Publisher: Frontiers Media SA
    Date: 2014
    Identifier: 2-88919-359-4 (ISBN)

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    Comment on "Bone Regulates Glucose Metabolism as an Endocrine Organ through Osteocalcin"

    Verma, Hitesh, Garg, Rajeev
    International journal of endocrinology, 2016, Vol.2016, pp.9724929 [Peer Reviewed Journal]
    MEDLINE/PubMed (U.S. National Library of Medicine)
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    Title: Comment on "Bone Regulates Glucose Metabolism as an Endocrine Organ through Osteocalcin"
    Author: Verma, Hitesh; Garg, Rajeev
    Is part of: International journal of endocrinology, 2016, Vol.2016, pp.9724929
    Identifier: 1687-8337 (ISSN); 27725833 Version (PMID)

    • Several versions

    Comment on “The Effect of Chromium Picolinate Supplementation on the Pancreas and Macroangiopathy in Type II Diabetes Mellitus Rats”

    Verma, Hitesh, Garg, Rajeev
    Journal of Diabetes Research, 2015, Vol.2015, 2 pages [Peer Reviewed Journal]

    • Several versions

    Comment on “Alpha-Lipoic Acid and Antioxidant Diet Help to Improve Endothelial Dysfunction in Adolescents with Type 1 Diabetes: A Pilot Trial”

    Verma, Hitesh, Garg, Rajeev
    Journal of Diabetes Research, 2015, Vol.2015, 2 pages [Peer Reviewed Journal]

    • Several versions

    Comment on “Bone Regulates Glucose Metabolism as an Endocrine Organ through Osteocalcin”

    Verma, Hitesh, Garg, Rajeev
    International Journal of Endocrinology, 2016, Vol.2016, 2 pages [Peer Reviewed Journal]

    • Several versions

    Pituitary apoplexy presenting with pure third ventricular bleed: A neurosurgical image

    Mohindra, Sandeep, Savardekar, Amey, Tripathi, Manjul, Garg, Rajeev
    Neurology India, 2012, Vol.60(3), p.314-315 [Peer Reviewed Journal]

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    Gastroretentive Floating Microspheres of Silymarin: Preparation and In Vitro Evaluation

    Garg, Rajeev, Gupta, G.D.
    Tropical Journal of Pharmaceutical Research, 2010, Vol.9(1) [Peer Reviewed Journal]
    Bioline International
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    Title: Gastroretentive Floating Microspheres of Silymarin: Preparation and In Vitro Evaluation
    Author: Garg, Rajeev; Gupta, G.D.
    Subject: Gastroretentive; Prolonged release; Silymarin; Floating microspheres; Ethyl cellulose; Hydroxypropyl methyl cellulose; Eudragit
    Description: Purpose: To prepare and evaluate floating microspheres of silymarin for prolonged gastric residence time and increased drug bioavailability. Methods: Cellulose microspheres - formulated with hydroxylpropyl methylcellulose (HPMC) and ethyl cellulose (EC) - and Eudragit microspheres - formulated with Eudragit® S 100 (ES) and Eudragit® RL (ERL) - were prepared by an emulsion-solvent evaporation method. The floating microspheres were evaluated for flow properties based on parameters such as angle of repose and compressibility index, as well as for various other physicochemical properties including particle size, incorporation efficiency, in vitro floatability, and in vitro drug release. The shape and surface morphology of the microspheres were characterised by optical and scanning electron microscopy. Results: Mean particle size increased while drug release rate decreased with increasing EC and ES contents of cellulose and Eudragit microspheres, respectively. Scanning electron microscopy showed pores on the surface and interior of the microspheres. The microspheres exhibited prolonged drug release for 12 h while still remained buoyant. Drug release kinetics, evaluated using the linear regression method, followed Higuchi kinetics and drug release mechanism was of the non-Fickian type. Conclusion: The developed floating microspheres of silymarin exhibited prolonged drug release in simulated gastric fluid for at least 12 h, and, therefore, could potentially improve the bioavailability of the drug as well as patient compliance.
    Is part of: Tropical Journal of Pharmaceutical Research, 2010, Vol.9(1)
    Identifier: 1596-5996 (ISSN)

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    Catheter-Based Near-Infrared Spectroscopy for Imaging of Lipid-Rich Plaques

    Garg, Rajeev, Waxman, Sergio
    Current Cardiovascular Imaging Reports, 2010, Vol.3(6), pp.403-411 [Peer Reviewed Journal]
    Springer Science & Business Media B.V.
    Available
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    Title: Catheter-Based Near-Infrared Spectroscopy for Imaging of Lipid-Rich Plaques
    Author: Garg, Rajeev; Waxman, Sergio
    Subject: Lipid-rich plaque ; Lipid core–containing coronary plaque ; Near-infrared spectroscopy ; Coronary artery disease
    Description: Lipid core–containing coronary plaques (LCPs), which cause most acute coronary syndromes and complications related to percutaneous coronary intervention (PCI), cannot be detected with coronary angiography. A near-infrared spectroscopy (NIRS) catheter-based system has been developed for intracoronary detection of LCP. The system was validated ex vivo in an autopsy study and in vivo in the multicenter SPECTACL study. Anecdotal case reports are emerging that hint at the clinical utility of this device in patients with coronary artery disease undergoing PCI in terms of predicting no-reflow, periprocedural myocardial infarction, or determining optimal stent length. However, it is not known whether widespread use of this device will translate into clinical benefit, a question which will need to be investigated in future studies. In this article, we review the evolution of NIRS technology in detection of LCP and the future direction of this imaging modality in optimizing the results of PCI.
    Is part of: Current Cardiovascular Imaging Reports, 2010, Vol.3(6), pp.403-411
    Identifier: 1941-9066 (ISSN); 1941-9074 (E-ISSN); 10.1007/s12410-010-9044-6 (DOI)

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    Leaking heart: ticking time bomb!

    Marella, Punnaiah, Hussein, Hassan, Rajpurohit, Naveen, Garg, Rajeev
    North American journal of medical sciences, October 2013, Vol.5(10), pp.620-2 [Peer Reviewed Journal]
    MEDLINE/PubMed (U.S. National Library of Medicine)
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    Title: Leaking heart: ticking time bomb!
    Author: Marella, Punnaiah; Hussein, Hassan; Rajpurohit, Naveen; Garg, Rajeev
    Subject: Acute Myocardial Infarction ; Echocardiography ; Pericardial Effusion ; Ventricular Free Wall Rupture
    Description: Cardiac rupture is a very important but under-recognized complication of acute myocardial infarction and usually happens within a week of the event. Sometimes it can be subacute and may not be typical of an acute blow out rupture. Hence careful evaluation is needed as a missed or delayed diagnosis can be fatal. An emergent echocardiogram may aid in immediate diagnosis. Surgery is the only treatment option and is mandatory despite the high mortality risk. An elderly male presented with dizziness and hypotension. Based on the timeline of his symptomatology, electrocardiographic abnormalities and labs, a subacute cardiac rupture was suspected in the emergency room itself. A high index of suspicion is needed to diagnose cardiac rupture. Subacute cases can be missed easily as presentation may not be dramatic. They can rapidly progress to a blowout rupture increasing mortality risk heavily even with surgical treatment.
    Is part of: North American journal of medical sciences, October 2013, Vol.5(10), pp.620-2
    Identifier: 2250-1541 (ISSN); 24350078 Version (PMID); 10.4103/1947-2714.120802 (DOI)

    • Several versions

    Primary extra-nodal non-Hodgkin's lymphoma of gingiva: A diagnostic dilemma

    Parihar, Sameer, Garg, Rajeev, Narain, Pooja
    Journal of Oral and Maxillofacial Pathology : JOMFP, May-Aug 2013, Vol.17(2), pp.320-320 [Peer Reviewed Journal]