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    • Several versions

    Combined adenovirus-mediated artificial microRNAs targeting mfgl2, mFas, and mTNFR1 protect against fulminant hepatic failure in mice

    Dong Xi, Ming Wang, Huali Ye, Xiaoping Luo, Qin Ning
    PloS one, 01 January 2013, Vol.8(11), p.e82330 [Peer Reviewed Journal]

    • Several versions

    Inhibition of intervertebral disc disease progression via the circPKNOX1–miR-370-3p–KIAA0355 axis

    Yizhen Huang, Jun Gao, Jianle Wang, Huali Ye, Teng Yao, Yining Xu, Zizheng Chen, Shuying Shen, Jianjun Ma
    Cell death discovery, 01 February 2021, Vol.7(1), pp.1-13 [Peer Reviewed Journal]

    • Several versions

    Circ0083429 Regulates Osteoarthritis Progression via the Mir-346/SMAD3 Axis

    Teng Yao, Teng Yao, Yute Yang, Yute Yang, Ziang Xie, Ziang Xie, Yining Xu, Yizhen Huang, Yizhen Huang, Jun Gao, Jun Gao, Shuying Shen, Shuying Shen, Huali Ye, Yasaman Iranmanesh, Shunwu Fan, Shunwu Fan, Jianjun Ma, Jianjun Ma
    Frontiers in cell and developmental biology, 01 January 2021, Vol.8 [Peer Reviewed Journal]

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    circCAMSAP1 promotes osteosarcoma progression and metastasis by sponging miR-145-5p and regulating FLI1 expression

    Zizheng Chen, Wenbin Xu, Deguang Zhang, Junjie Chu, Shuying Shen, Yan Ma, Qingxin Wang, Gang Liu, Teng Yao, Yizhen Huang, Huali Ye, Jiying Wang, Jianjun Ma, Shunwu Fan
    Molecular therapy. Nucleic acids, 01 March 2021, Vol.23, pp.1120-1135 [Peer Reviewed Journal]
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    Title: circCAMSAP1 promotes osteosarcoma progression and metastasis by sponging miR-145-5p and regulating FLI1 expression
    Author: Zizheng Chen; Wenbin Xu; Deguang Zhang; Junjie Chu; Shuying Shen; Yan Ma; Qingxin Wang; Gang Liu; Teng Yao; Yizhen Huang; Huali Ye; Jiying Wang; Jianjun Ma; Shunwu Fan
    Subject: Anatomy & Physiology
    Description: Osteosarcoma is the most common primary malignant bone tumor in adolescents. While chemotherapy combined with surgery can improve the prognosis of some patients, chemo-resistance is still a huge obstacle in osteosarcoma treatment. Accumulating evidence demonstrates that circular RNAs (circRNAs) are involved in cancer progression and metastasis, but their specific role in osteosarcoma remains mostly undescribed. In this study, we performed circRNA deep sequencing and identified 88 distinct circRNAs from a human osteosarcoma cell lines group (143B, HOS, SJSA, and U2OS) and the human osteoblast hFOB 1.19 (control). We found that circCAMSAP1, also named hsa_circ_0004338, is significantly upregulated in human osteosarcoma tissues and cell lines, and it is positively correlated with osteosarcoma development. Silencing of circCAMSAP1 effectively suppresses osteosarcoma cell growth, apoptosis, migration, and invasion. Furthermore, we validated that circCAMSAP1 functions in osteosarcoma...
    Is part of: Molecular therapy. Nucleic acids, 01 March 2021, Vol.23, pp.1120-1135
    Identifier: 2162-2531 (ISSN); 2162-2531 (E-ISSN)