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    • Several versions

    Genomic insights into the broad antifungal activity, plant-probiotic properties, and their regulation, in Pseudomonas donghuensis strain SVBP6

    Agaras, Betina Cecilia, Iriarte, Andrés, Valverde, Claudio Fabián
    PLoS ONE, 2018, Vol.13(3) [Peer Reviewed Journal]

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    Est10: A Novel Alkaline Esterase Isolated from Bovine Rumen Belonging to the New Family XV of Lipolytic Enzymes

    Rodríguez, María Cecilia, Loaces, Inés, Amarelle, Vanesa, Senatore, Daniella, Iriarte, Andrés, Fabiano, Elena, Noya, Francisco
    PLoS ONE, 2015, Vol.10(5) [Peer Reviewed Journal]

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    Comparison of transcriptomic landscapes of different lamb muscles using RNA-Seq

    Armstrong, Eileen, Iriarte, Andres, Nicolini, Paula, De Los Santos, Jorge, Ithurralde, Javier, Bielli, Alejandro, Bianchi, Gianni, Peñagaricano, Francisco
    PloS one, 2018, Vol.13(7), pp.e0200732 [Peer Reviewed Journal]

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    The Genetic Analysis of an Acinetobacter johnsonii Clinical Strain Evidenced the Presence of Horizontal Genetic Transfer

    Montaña, Sabrina, Schramm, Sareda T. J, Traglia, German Matías, Chiem, Kevin, Parmeciano Di Noto, Gisela, Almuzara, Marisa, Barberis, Claudia, Vay, Carlos, Quiroga, Cecilia, Tolmasky, Marcelo E, Iriarte, Andrés, Ramírez, María Soledad
    PLoS ONE, 2016, Vol.11(8) [Peer Reviewed Journal]

    • Several versions

    Draft Genome Sequence of Cupriavidus UYMMa02A, a Novel Beta-Rhizobium Species

    Iriarte, Andrés, Platero, Raúl, Romero, Valeria, Fabiano, Elena, Sotelo-Silveira, José R
    Genome announcements, 10 November 2016, Vol.4(6) [Peer Reviewed Journal]

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    General Trends in Selectively Driven Codon Usage Biases in the Domain Archaea

    Iriarte, Andrés, Jara, Eugenio, Leytón, Lucía, Diana, Leticia, Musto, Héctor
    Journal of Molecular Evolution, 2014, Vol.79(3), pp.105-110 [Peer Reviewed Journal]

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    Genome analysis of a clinical isolate of Shewanella sp. uncovered an active hybrid integrative and conjugative element carrying an integron platform inserted in a novel genomic locus

    Parmeciano Di Noto, Gisela, Jara, Eugenio, Iriarte, Andrés, Centrón, Daniela, Quiroga, Cecilia
    Microbiology (Reading, England), August 2016, Vol.162(8), pp.1335-1345 [Peer Reviewed Journal]
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    Title: Genome analysis of a clinical isolate of Shewanella sp. uncovered an active hybrid integrative and conjugative element carrying an integron platform inserted in a novel genomic locus
    Author: Parmeciano Di Noto, Gisela; Jara, Eugenio; Iriarte, Andrés; Centrón, Daniela; Quiroga, Cecilia
    Subject: Bacterial Proteins -- Genetics ; Drug Resistance, Multiple, Bacterial -- Genetics ; Gene Transfer, Horizontal -- Genetics ; Integrons -- Genetics ; Membrane Transport Proteins -- Genetics ; Shewanella -- Genetics ; Beta-Lactamases -- Genetics
    Description: Shewanella spp. are currently considered to be emerging pathogens that can code for a blaOXA carbapenemase in their chromosome. Complete genome analysis of the clinical isolate Shewanella sp. Sh95 revealed that this strain is a novel species, which shares a lineage with marine isolates. Characterization of its resistome showed that it codes for genes drfA15, qacH and blaOXA-48. We propose that Shewanella sp. Sh95 acts as reservoir of blaOXA-48. Moreover, analysis of mobilome showed that it contains a novel integrative and conjugative element (ICE), named ICESh95. Comparative analysis between the close relatives ICESpuPO1 from Shewanella sp. W3-18-1 and ICE SXTMO10 from Vibrio cholerae showed that ICESh95 encompassed two new regions, a type III restriction modification system and a multidrug resistance integron. The integron platform contained a novel arrangement formed by gene cassettes drfA15 and qacH, and a class C-attC group II intron. Furthermore, insertion of ICESh95 occurred at a...
    Is part of: Microbiology (Reading, England), August 2016, Vol.162(8), pp.1335-1345
    Identifier: 1465-2080 (E-ISSN); 27215217 Version (PMID); 10.1099/mic.0.000310 (DOI)

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    Evolution of optimal codon choices in the family Enterobacteriaceae

    Iriarte, Andrés, Baraibar, Juan Diego, Romero, Héctor, Castro-Sowinski, Susana, Musto, Héctor
    Microbiology (Reading, England), March 2013, Vol.159(Pt 3), pp.555-564 [Peer Reviewed Journal]
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    Title: Evolution of optimal codon choices in the family Enterobacteriaceae
    Author: Iriarte, Andrés; Baraibar, Juan Diego; Romero, Héctor; Castro-Sowinski, Susana; Musto, Héctor
    Subject: Codon ; Protein Biosynthesis ; Enterobacteriaceae -- Genetics
    Description: The Enterobacteriaceae are a large family of Proteobacteria that include many well-known prokaryotic genera, such as Escherichia, Yersinia and Salmonella. The main ideas of synonymous codon usage (CU) evolution and translational selection have been deeply influenced by studies with these bacterial groups. In this work we report the analysis of the CU pattern of completely sequenced bacterial genomes that belong to the Enterobacteriaceae. The effect of selection in translation acting at the levels of speed and accuracy, and phylogenetic trends within this group are described. Preferred (optimal) codons were identified. The evolutionary dynamics of these codons were studied and following a Bayesian approach these preferences were traced back to the common ancestor of the family. We found that there is some level of variation in selection among the analysed micro-organisms that is probably associated with lineage-specific trends. The codon bias was largely conserved across the evolutionary...
    Is part of: Microbiology (Reading, England), March 2013, Vol.159(Pt 3), pp.555-564
    Identifier: 1465-2080 (E-ISSN); 23288542 Version (PMID); 10.1099/mic.0.061952-0 (DOI)

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    Pandemic influenza A virus codon usage revisited: biases, adaptation and implications for vaccine strain development

    Goñi Natalia, Iriarte Andrés, Comas Victoria, Soñora Martín, Moreno Pilar, Moratorio Gonzalo, Musto Héctor, Cristina Juan
    Virology journal, 01 November 2012, Vol.9(1), p.263 [Peer Reviewed Journal]
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    Title: Pandemic influenza A virus codon usage revisited: biases, adaptation and implications for vaccine strain development
    Author: Goñi Natalia; Iriarte Andrés; Comas Victoria; Soñora Martín; Moreno Pilar; Moratorio Gonzalo; Musto Héctor; Cristina Juan
    Subject: Influenza A Virus ; Codon Usage ; Evolution ; Medicine ; Biology
    Description: Abstract Background Influenza A virus (IAV) is a member of the family Orthomyxoviridae and contains eight segments of a single-stranded RNA genome with negative polarity. The first influenza pandemic of this century was declared in April of 2009, with the emergence of a novel H1N1 IAV strain (H1N1pdm) in Mexico and USA. Understanding the extent and causes of biases in codon usage is essential to the understanding of viral evolution. A comprehensive study to investigate the effect of selection pressure imposed by the human host on the codon usage of an emerging, pandemic IAV strain and the trends in viral codon usage involved over the pandemic time period is much needed. Results We performed a comprehensive codon usage analysis of 310 IAV strains from the pandemic of 2009. Highly biased codon usage for Ala, Arg, Pro, Thr and Ser were found. Codon usage is strongly influenced by underlying biases in base composition. When correspondence analysis (COA) on relative synonymous codon...
    Is part of: Virology journal, 01 November 2012, Vol.9(1), p.263
    Identifier: 1743-422X (ISSN); 1743-422X (E-ISSN); 10.1186/1743-422X-9-263 (DOI)

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    Pandemic influenza A virus codon usage revisited: biases, adaptation and implications for vaccine strain development

    Goñi, Natalia, Iriarte, Andrés, Comas, Victoria, Soñora, Martín, Moreno, Pilar, Moratorio, Gonzalo, Musto, Héctor, Cristina, Juan
    Virology Journal, 2012, Vol.9, p.263 [Peer Reviewed Journal]