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    • Several versions

    Microneedle Coating Techniques for Transdermal Drug Delivery

    Haj-Ahmad, Rita, Khan, Hashim, Arshad, Muhammad, Rasekh, Manoochehr, Hussain, Amjad, Walsh, Susannah, Li, Xiang, Chang, Ming-Wei, Ahmad, Zeeshan
    Pharmaceutics, Vol.7(4), pp.486-502 [Peer Reviewed Journal]

    • Several versions

    Pricing of Risk, Various Volatility Dynamics and Macroeconomic Exposure of Firm Returns: New Evidence on Age Effect

    Khan, Faisal, Khan, Hashim
    International Journal of Economics and Financial Issues, 2016, Vol.6(2) [Peer Reviewed Journal]

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    Relationship between decision making styles and consumer behavior

    Hunjra, Ahmed, Khan, Hashim
    IDEAS Working Paper Series from RePEc, 2011
    © ProQuest LLC All rights reserved, ABI/INFORM Global, ABI/INFORM Global (Alumni edition), Publicly Available Content Database, ABI/INFORM Complete, ProQuest Central, ABI/INFORM Collection (Alumni edition), ProQuest Business Collection, Business Premium Collection, Business Premium Collection (Alumni edition), ProQuest Central (new), ProQuest Central Korea, ProQuest Central Essentials, ProQuest One Academic
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    Title: Relationship between decision making styles and consumer behavior
    Author: Hunjra, Ahmed; Khan, Hashim
    Subject: Ideas.Repec.Org/P/Pra/Mprapa/40676.Html
    Description: The objective of this study is to identify the different factors that impact on consumer behavior on the bases of decision making style. The sample size of this study was two hundred and fifty. Data was collected through five point Likert scale questionnaire. SPSS was used to analyze the data. Correlation and multiple regression was performed to measure the relationship between independent and dependent variables and independent sample t-test was applied to test difference between male and female decision making style. This study concludes that there is significant relationship between male and female decision making style and female respondents are more agreed that decision making styles influence the consumer behavior. All the independent variables have significant and positive relationship with consumer behavior.
    Is part of: IDEAS Working Paper Series from RePEc, 2011

    • Several versions

    Pricing of risk and volatility dynamics on an emerging stock market: evidence from both aggregate and disaggregate data

    Khan, Faisal, Rehman, Saif-Ur, Khan, Hashim, Xu, Tie
    Ekonomska istraživanja, 01 January 2016, Vol.29(1), pp.799-815 [Peer Reviewed Journal]

    • Several versions

    Design of a broadband current mode class-D power amplifier with harmonic suppression

    Khan, Hashim, Qureshi, Abdul, Zafar, Faiza, Wahab, Qamar
    Analog Integrated Circuits and Signal Processing, 2016, Vol.89(1), pp.15-24 [Peer Reviewed Journal]

    • Several versions

    A parallel circuit differential class-E power amplifier using series capacitance

    Khan, Hashim, Fritzin, Jonas, Alvandpour, Atila, Wahab, Qamar
    Analog Integrated Circuits and Signal Processing, 2013, Vol.75(1), pp.31-40 [Peer Reviewed Journal]

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    The effectiveness of prophylactic proton pump inhibitors for prevention of non-steroidal anti inflammatory drugs associated gastric and duodenal ulcers in elderly

    Kheiri, Babikir, Mabrouk, Ahmed, Ahmed, Imran, Khan, Hashim, Sheikh, Azeem S
    Quality in primary care, 2014, Vol.22(6), pp.282-4 [Peer Reviewed Journal]
    MEDLINE/PubMed (U.S. National Library of Medicine)
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    Title: The effectiveness of prophylactic proton pump inhibitors for prevention of non-steroidal anti inflammatory drugs associated gastric and duodenal ulcers in elderly
    Author: Kheiri, Babikir; Mabrouk, Ahmed; Ahmed, Imran; Khan, Hashim; Sheikh, Azeem S
    Description: Aims was undertaken to ensure concomitant usage of proton pump inhibitors (PPIs) with Non-Steroidal Anti-inflammatory Drugs (NSAIDs) in Elderly, in order to avoid upper gastrointestinal (GI) symptoms and ulcers. Reviewing of 386 patients' prescription on the EMIS (Egton Medical Information Systems) Web, on April 2014. Checking who have not been prescribed PPIs with NSAIDs, offering them appointment for prescription and discussion about risks and benefits of PPIs. Re-audit of 390 patients' prescription on the EMIS Web, on July 2014. Exclusion criteria in the audit and re-audit were; NSAIDs usage for more than 3 years, contra-indications for PPIs, and patients who declined inclusion in the audit. In the first audit cycle, a total of 386 patients' prescription reviewed, 23 (6%) patients were not prescribed PPIs with NSAIDs and were eligible for PPIs prescription. Those patients were contacted by post, an appointment arranged for them and prescribed the PPIs. 12 weeks later a re-audit was done, showed that all patients (100%) who are prescribed NSAIDs are prescribed prophylactic PPIs. None of the patients who are prescribed NSAIDs and PPIs concomitantly developed upper GI symptoms or ulcers. The audit increased the awareness of the junior doctors of the importance of concomitant prescription of PPIs with NSAIDs, in accordance with the electronic Medical Compendium (eMC) guidelines, to prevent upper GI symptoms and ulcers. That was reflected in the re-audit having 100% of the patients prescribed NSAIDs and PPIs concomitantly.
    Is part of: Quality in primary care, 2014, Vol.22(6), pp.282-4
    Identifier: 1479-1072 (ISSN); 25887654 Version (PMID)

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    Institutions, macroeconomic policy and foreign direct investment: South Asian countries case

    Azam, Muhammad, Khan, Hashim, Hunjra, Ahmed, Ahmad, H, Chani, Muhammad
    IDEAS Working Paper Series from RePEc, 2011
    © ProQuest LLC All rights reserved, ABI/INFORM Global, ABI/INFORM Global (Alumni edition), Publicly Available Content Database, ABI/INFORM Complete, ProQuest Central, ABI/INFORM Collection (Alumni edition), ProQuest Business Collection, Business Premium Collection, Business Premium Collection (Alumni edition), ProQuest Central (new), ProQuest Central Korea, ProQuest Central Essentials, ProQuest One Academic
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    Title: Institutions, macroeconomic policy and foreign direct investment: South Asian countries case
    Author: Azam, Muhammad; Khan, Hashim; Hunjra, Ahmed; Ahmad, H; Chani, Muhammad
    Subject: Ideas.Repec.Org/P/Pra/Mprapa/32480.Html
    Description: Recent economic literature suggests that institutional quality factors exerted positive effect on foreign direct investment (FDI) inflows. The main focus of this study is to examine the role of institutional factors and macro economic policy factors on FDI inflows in a panel data of seven South Asian countries over the period of 12 years since 1996-2007. This study implies that a good institutional quality plays a key role in attractiveness of FDI inflows. A poor macroeconomic policy situation produces negative impact on FDI. Good Institutional quality and macroeconomic policy generate negative in a combined form on FDI. This study further implies that poor economic policy deteriorates institutional quality and creates negative effect on FDI inflows. Incredibility in trade liberalization policy may be a part of poor macro economic policy.
    Is part of: IDEAS Working Paper Series from RePEc, 2011

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    P2Y Nucleotide Receptor Prompts Human Cardiac Progenitor Cell Activation by Modulating Hippo Signaling

    Khalafalla, Farid G, Greene, Steven, Khan, Hashim, Ilves, Kelli, Monsanto, Megan M, Alvarez, Roberto, Chavarria, Monica, Nguyen, Jonathan, Norman, Benjamin, Dembitsky, Walter P, Sussman, Mark A
    Circulation research, 10 November 2017, Vol.121(11), pp.1224-1236 [Peer Reviewed Journal]
    MEDLINE/PubMed (U.S. National Library of Medicine)
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    Title: P2Y Nucleotide Receptor Prompts Human Cardiac Progenitor Cell Activation by Modulating Hippo Signaling
    Author: Khalafalla, Farid G; Greene, Steven; Khan, Hashim; Ilves, Kelli; Monsanto, Megan M; Alvarez, Roberto; Chavarria, Monica; Nguyen, Jonathan; Norman, Benjamin; Dembitsky, Walter P; Sussman, Mark A
    Subject: Adult Stem Cells ; Heart Failure ; Nucleotides ; Cell Proliferation ; Signal Transduction ; Adult Stem Cells -- Metabolism ; Myocytes, Cardiac -- Metabolism ; Protein-Serine-Threonine Kinases -- Metabolism ; Receptors, Purinergic P2y2 -- Metabolism
    Description: Autologous stem cell therapy using human c-Kit cardiac progenitor cells (hCPCs) is a promising therapeutic approach for treatment of heart failure (HF). However, hCPCs derived from aged patients with HF with genetic predispositions and comorbidities of chronic diseases exhibit poor proliferative and migratory capabilities, which impair overall reparative potential for injured myocardium. Therefore, empowering functionally compromised hCPCs with proregenerative molecules ex vivo is crucial for improving the therapeutic outcome in patients with HF. To improve hCPC proliferation and migration responses that are critical for regeneration by targeting proregenerative P2Y nucleotide receptor (P2YR) activated by extracellular ATP and UTP molecules released following injury/stress. c-Kit hCPCs were isolated from cardiac tissue of patients with HF undergoing left ventricular assist device implantation surgery. Correlations between P2 nucleotide receptor expression and hCPC growth kinetics revealed downregulation of select P2 receptors, including P2YR, in slow-growing hCPCs compared with fast growers. hCPC proliferation and migration significantly improved by overexpressing or stimulating P2YR. Mechanistically, P2YR-induced proliferation and migration were dependent on activation of YAP (yes-associated protein)-the downstream effector of Hippo signaling pathway. Proliferation and migration of functionally impaired hCPCs are enhanced by P2YR-mediated YAP activation, revealing a novel link between extracellular nucleotides released during injury/stress and Hippo signaling-a central regulator of cardiac regeneration. Functional correlations exist between hCPC phenotypic properties and P2 purinergic receptor expression. Lack of P2YR and other crucial purinergic stress detectors could compromise hCPC responsiveness to presence of extracellular stress signals. These findings set the stage for subsequent studies to assess purinergic signaling modulation as a potential strategy to improve therapeutic outcome for use of hCPCs in patients with HF.
    Is part of: Circulation research, 10 November 2017, Vol.121(11), pp.1224-1236
    Identifier: 1524-4571 (E-ISSN); 28923792 Version (PMID); 10.1161/CIRCRESAHA.117.310812 (DOI)

    • Several versions

    Personality Dynamism and Academic Performance Among Boarders and Non-boarders Studying in a Medical University

    Khan, Muhammad Sarfraz, Malik, Abdur Rehman, Ashraf Butt, Adam Umair, Khalid, Areeb, Maqbool, Shahzaib, Khan, Hashim, Younas, Muhammad Waqar
    Cureus, 03 July 2019, Vol.11(7), pp.e5072 [Peer Reviewed Journal]