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From neuron to brain / John G. Nicholls ... [et al.]
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From neuron to brain / John G. Nicholls ... [et al.]
[Contents]. - Introduction. - Principles of Signaling and Organization. - Organization of the Retina. - Signaling in Nerve Cells. - Cellular and Molecular Biology of Neurons. - Signals for Development of the Nervous System. - Regeneration of the Nervous System after Injury. - II. Signaling in the Nervous System. - Membrane Proteins and Their Function. - Ion Channels and Signaling. - Properties of Ion Channels. - Measurement of Single-Channel Currents. - Measuring Channel Conductance. - Structure of Ion Channels. - The Nicotinic Acetylcholine Receptor. - A Receptor Superfamily. - Voltage-Activated Channels. - Other Channels. - Diversity of Subunits. - Conclusion. - Cloning Receptors and Channels. - Classification of Amino Acids. - Expression of Receptors and Channels in Xenopus Oocytes. - Transport across Cell Membranes. - The Sodium-Potassium Exchange Pump. - Calcium Pumps. - Sodium-Calcium Exchange. - Chloride Transport. - Transport of Neurotransmitters. - Molecular Structure of Transporters. - Significance of Transport Mechanisms. - Properties of Neurons and Glia. - Ionic Basis of the Resting Potential. - A Model Cell. - Membrane Potentials in Squid Axons. - Changes in Membrane Potential. - Ionic Basis of the Action Potential. - Sodium and Potassium Currents. - Voltage Clamp Experiments. - The Role of Calcium in Excitation. - The Voltage Clamp. - Neurons as Conductors of Electricity. - Passive Electrical Properties of Nerve and Muscle Membranes. - Propagation of Action Potentials. - Conduction in Dendrites. - Pathways for Current Flow between Cells. - Electrotonic Potentials and the Membrane Time Constant. - Classification of Nerve Fibers in Vertebrates. - Stimulating and Recording with External Electrodes. - Current Flow between Cells. - Properties and Functions of Neuroglial Cells. - Physiological Properties of Neuroglial Cell Membranes. - Functions of Neuroglial Cells. - Effects of Neuronal Activity on Glial Cells. - Glial Cells and the Blood-Brain Barrier. - Glial Cells and Immune Responses of the CNS. - The Blood-Brain Barrier. - Communication between Excitable Cells. - Principles of Direct Synaptic Transmission. - Nerve Cells and Synaptic Connections. - Electrical Synaptic Transmission. - Chemical Synaptic Transmission. - Direct Synaptic Inhibition. - Electrical Model of the Motor End Plate. - Indirect Mechanisms of Synaptic Transmission. - Metabotropic Receptors and G Proteins. - Direct Modulation of Channel Function by G Proteins. - G Protein Activation of Cytoplasmic Second Messenger Systems. - Calcium as an Intracellular Second Messenger. - Prolonged Time Course of Indirect Transmitter Action. - Identifying Responses Mediated by G Proteins. - Cyclic AMP as a Second Messenger. - Diacylglycerol and IP as Second Messengers. - Formation and Metabolism of Arachidonic Acid. - Transmitter Release. - Characteristics of Transmitter Release. - Quantal Release. - Vesicle Hypothesis of Transmitter Release. - Synaptic Plasticity. - Short-Term Changes in Signaling. - Long-Term Changes in Signaling. - Cellular and Molecular Biochemistry of Synaptic Transmission. - Neurotransmitters. - Neurotransmitter Synthesis. - Storage of Transmitters in Synaptic Vesicles. - Axonal Transport. - Transmitter Release and Vesicle Recycling. - Transmitter Receptor Localization. - Removal of Transmitters from the Synaptic Cleft. - The SNARE Hypothesis. - Neurotransmitters in the Central Nervous System. - Mapping Transmitter Distribution. - Peptide Transmitters in the CNS. - Regulation of Central Nervous System Function by Biogenic Amines. - Molecular Methods and CNS Transmitters. - Integrative Mechanisms. - Circuits Mediating Stereotyped Behavior. - Cellular Mechanisms of Integration and Behavior in Leeches, Ants, and Bees. - From Neurons to Behavior and Vice Versa. - Integration by Individual Neurons in the CNS of the Leech. - Navigation by Ants and Bees. - Why Should One Work on Invertebrate Nervous Systems?. - Autonomic Nervous System. - Functions under Involuntary Control. - Synaptic Transmission by Postganglionic Axons. - The Path to Understanding Sympathetic Mechanisms. - Acquisition and Analysis of Sensory Information. - Transduction of Mechanical and Chemical Stimuli. - Stimulus Coding by Mechanoreceptors. - Transduction of Mechanical Stimuli. - Olfaction. - Mechanisms of Taste (Gustation). - Transduction of Nociceptive and Thermal Stimuli. - Sensory Epithelia of the Inner Ear. - Processing of Somatosensory and Auditory Signals. - The Somatosensory System: Tactile Recognition. - The Auditory System: Encoding Sound Frequency. - Brodmann's Areas. - The Visual System. - Transduction and Signaling in the Retina. - The Eye. - The Retina. - Visual Pigments. - Transduction by Photoreceptors. - Transmission from Photoreceptors to Bipolar Cells. - Receptive Fields of Ganglion Cells. - Adaptation of Photoreceptors. - Analysis of Form in Primary Visual Cortex. - The Lateral Geniculate Nucleus. - Cytoarchitecture of the Cortex. - Strategies for Exploring the Cortex. - Functional Architecture of the Visual Cortex. - Ocular Dominance Slabs. - The Integration of Visual Information. - Where Do We Go from Here?. - Color Constancy. - Corpus Callosum. - Initiation and Control of Movement. - Cellular Mechanisms of Motor Control. - The Motor Unit. - Spinal Reflexes. - Generation of Coordinated Movement. - Motor Cortex and the Execution of Voluntary Movement. - The Cerebellum. - The Basal Ganglia. - ..Extracellular Recording of Motor Activity. - Development of the Nervous System. - Development of the Nervous System. - Early Neural Morphogenesis. - Regional Specification of Neural Tissue. - Determination of Neuronal and Glial Cell Identity. - Axon Outgrowth. - Axon Guidance. - Target Innervation. - Synapse Formation. - Growth Factors and Survival of Neurons. - Competitive Interactions during Development. - General Considerations of Neural Specificity. - Discovery of Nerve Growth Factor. - Denervation and Regeneration of Synaptic Connections. - Changes in Axotomized Neurons and the Surrounding Glial Cells. - Effects of Denervation on Postsynaptic Cells. - Regeneration in the Vertebrate Peripheral Nervous System. - Role of Basal Lamina at Regenerating Synapses. - Regeneration in the Mammalian CNS. - Critical Periods in Visual and Auditory Systems. - The Visual System in Newly Born Monkeys and Kittens. - Effects of Abnormal Experience in Early Life. - Requirements for Maintenance of Functioning Connections in the Visual System. - Cellular and Molecular Mechanisms of Deprivation Changes. - Critical Periods in the Auditory System. - Critical Periods for Higher Functions. - Conclusion. - Open Questions. - Appendix A: Current Flow in Electrical Circuits. - Appendix B: Metabolic Pathways for the Synthesis and Inactivation of Low-Molecular-Weight Transmitters. - Appendix C: Structures and Pathways of the Brain.
2e éd.: From neuron to brain : a cellular approach to the function of the nervous system / Stephen W. Kuffler, John G. Nicholls, A. Robert Martin. - 1984