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    • Article
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    Application of Kriging Interpolation for Glacier Mass Balance Computations

    Hock, Regine, Jensen, Holger
    Geografiska Annaler. Series A, Physical Geography, 1 January 1999, Vol.81(4), pp.611-619 [Revue évaluée par les pairs]
    Archival Journals (JSTOR)
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    Titre: Application of Kriging Interpolation for Glacier Mass Balance Computations
    Auteur: Hock, Regine; Jensen, Holger
    Description: In order to compute the specific mass balance of a glacier, point measurements of mass balance need to be integrated and thus interpolated over the entire glacier. In this study kriging was applied as interpolation technique to mass balance data of Storglaciären, a 3 km 2 valley glacier, focusing on the sensitivity of results to the choice of some kriging parameters. Although the spatial means varied only little in most cases, the spatial distribution of the mass balance quantities was sensitive to the assumption on kriging parameters, suggesting that the kriging parameters need to be carefully optimized for each case if the spatial distribution is of interest.
    Fait partie de: Geografiska Annaler. Series A, Physical Geography, 1 January 1999, Vol.81(4), pp.611-619
    Identifiant: 04353676 (ISSN); 14680459 (E-ISSN)

    • Livre
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    Räumliche Interpolation der Stundenwerte von Niederschlag, Temperatur und Schneehöhe

    Jensen, Holger
    Zürich : Geographisches Institut ; Eidgenössische Technische Hochschule
    1989
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    Titre: Räumliche Interpolation der Stundenwerte von Niederschlag, Temperatur und Schneehöhe / Holger Jensen
    Auteur: Jensen, Holger
    Editeur: Zürich : Geographisches Institut ; Eidgenössische Technische Hochschule
    Date: 1989
    Collation: 70 p. : ill. ; 30 cm
    Collection: Zürcher geographische Schriften ; 35
    Documents dans cette collection: Zürcher Geographische Schriften
    Sujet RERO: Climat - variable régionalisée - Méthodologie
    Classification: LC QC866
    Identifiant: 3728116785 (ISBN)
    No RERO: 1151959
    Permalien:
    http://data.rero.ch/01-1151959/html?view=FR_V1

    • Plusieurs versions

    In vitro evaluation of avidin antibody pretargeting using 211 At‐labeled and biotinylated poly‐L‐lysine as effector molecule

    Frost, Sofia Hl, Jensen, Holger, Lindegren, Sture
    Cancer, 15 February 2010, Vol.116(S4), pp.1101-1110 [Revue évaluée par les pairs]

    • Plusieurs versions

    Astatine-211 labeling: a study towards automatic production of astatinated antibodies

    Aneheim, Emma, Jensen, Holger, Albertsson, Per, Lindegren, Sture
    Journal of Radioanalytical and Nuclear Chemistry, 2015, Vol.303(1), pp.979-983 [Revue évaluée par les pairs]

    • Plusieurs versions

    Extraction of 211 At from nitric acid solutions into various organic solvents for use as an α -source for radiation chemistry studies

    Ekberg, Christian, Jensen, Holger, Mezyk, Stephen, Mincher, Bruce, Skarnemark, Gunnar
    Journal of Radioanalytical and Nuclear Chemistry, 2017, Vol.314(1), pp.235-239 [Revue évaluée par les pairs]

    • Plusieurs versions

    N-[2-(maleimido)ethyl]-3-(trimethylstannyl)benzamide, a molecule for radiohalogenation of proteins and peptides

    Aneheim, Emma, Foreman, Mark R. Stj, Jensen, Holger, Lindegren, Sture
    Applied radiation and isotopes, February 2015, Vol.96, pp.1-5 [Revue évaluée par les pairs]

    • Plusieurs versions

    Intraperitoneal Alpha-Radioimmunotherapy of Advanced Ovarian Cancer in Nude Mice Using Different High Specific Activities

    Elgqvist, Jorgen, Ahlberg, Daniel, Andersson, Hakan, Jensen, Holger, Johansson, Bengt R, Kahu, Helena, Olsson, Marita, Lindegren, Sture
    World journal of oncology, June 2010, Vol.1(3), pp.101-110 [Revue évaluée par les pairs]

    • Plusieurs versions

    Repeated Intraperitoneal alpha-Radioimmunotherapy of Ovarian Cancer in Mice

    Elgqvist, Jörgen, Andersson, Håkan, Jensen, Holger, Kahu, Helena, Lindegren, Sture, Warnhammar, Elisabet, Hultborn, Ragnar
    Journal of oncology, 2010, Vol.2010, pp.394913 [Revue évaluée par les pairs]

    • Plusieurs versions

    Tsalen- and Tsalpn-Based Nickel Complexes with Two Aldehyde Functionalities as Potential Synthons for Thiophenolate-Containing Di- and Polynucleating Acyclic and Macrocyclic Ligands

    Christensen, Aase, Jensen, Holger S, Mckee, Vickie, Mckenzie, Christine J, Munch, Maria
    Inorganic chemistry, 17 December 1997, Vol.36(26), pp.6080-6085 [Revue évaluée par les pairs]

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    Astatine-211-labeled antibodies for treatment of disseminated ovarian cancer: an overview of results in an ovarian tumor model

    Andersson, Håkan, Elgqvist, Jörgen, Horvath, György, Hultborn, Ragnar, Jacobsson, Lars, Jensen, Holger, Karlsson, Börje, Lindegren, Sture, Palm, Stig
    Clinical cancer research : an official journal of the American Association for Cancer Research, 01 September 2003, Vol.9(10 Pt 2), pp.3914S-21S [Revue évaluée par les pairs]
    MEDLINE/PubMed (U.S. National Library of Medicine)
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    Titre: Astatine-211-labeled antibodies for treatment of disseminated ovarian cancer: an overview of results in an ovarian tumor model
    Auteur: Andersson, Håkan; Elgqvist, Jörgen; Horvath, György; Hultborn, Ragnar; Jacobsson, Lars; Jensen, Holger; Karlsson, Börje; Lindegren, Sture; Palm, Stig
    Sujet: Astatine -- Therapeutic Use ; Isotopes -- Therapeutic Use ; Ovarian Neoplasms -- Radiotherapy ; Radioimmunotherapy -- Methods
    Description: The aim of the study was to establish and refine a preclinical model to alpha-immunoradiotherapy of ovarian cancer. At-211 was produced by cyclotron irradiation of a bismuth-209 target and isolated using a novel dry distillation procedure. Monoclonal antibodies were radiohalogenated with the intermediate reagent N-succinimidyl 3-(trimethylstannyl)benzoate and characterized in terms of radiochemical yield and in vitro binding properties. In vitro OVCAR-3 cells were irradiated using an external Cobalt-60 beam, as reference, or At-211-albumin and labeled antibody. Growth assays were used to establish cell survival. A Monte Carlo program was developed to simulate the energy imparted and the track length distribution. Nude mice were used for studies of WBC depression, with various activities of Tc-99m antibodies, as reference, and At-211 antibodies. In efficacy studies, OVCAR-3 cells were inoculated i.p., and animals were treated 2 weeks later. The animals were either dissected 6 weeks later or followed-up for long-term survival. A rapid distillation procedure, as well as a rapid and high-yield, single-pot labeling procedure, was achieved. From growth inhibition data, the relative biological effectiveness of the alpha-emission for OVCAR-3 cells was estimated to be approximately 5, which is in the same range as found in vivo for hematological toxicity. At-211 MOv18 was found to effectively inhibit the development of tumors and ascites, also resulting in long-term survival without significant toxic effect. Use of the short-range, high-linear energy transfer alpha-emitter At-211 conjugated to a surface epitope-recognizing monoclonal antibody appears to be highly efficient without significant toxicity in a mouse peritoneal tumor model, urging a Phase I clinical trial.
    Fait partie de: Clinical cancer research : an official journal of the American Association for Cancer Research, 01 September 2003, Vol.9(10 Pt 2), pp.3914S-21S
    Identifiant: 1078-0432 (ISSN); 14506189 Version (PMID)