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    • Plusieurs versions

    Dry-distillation of astatine-211 from irradiated bismuth targets: a time-saving procedure with high recovery yields

    Lindegren, Sture, Bäck, Tom, Jensen, Holger J
    Applied radiation and isotopes, 2001, Vol.55(2), pp.157-160 [Revue évaluée par les pairs]

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    Absorbed Doses and Risk Estimates of 211At-MX35 F(ab')2 in Intraperitoneal Therapy of Ovarian Cancer Patients

    Cederkrantz, Elin, Andersson, Håkan, Bernhardt, Peter, Bäck, Tom, Hultborn, Ragnar, Jacobsson, Lars, Jensen, Holger, Lindegren, Sture, Ljungberg, Michael, Magnander, Tobias, Palm, Stig, Albertsson, Per
    International journal of radiation oncology, biology, physics, 01 November 2015, Vol.93(3), pp.569-576 [Revue évaluée par les pairs]

    • Plusieurs versions

    N-[2-(maleimido)ethyl]-3-(trimethylstannyl)benzamide, a molecule for radiohalogenation of proteins and peptides

    Aneheim, Emma, Foreman, Mark R. Stj, Jensen, Holger, Lindegren, Sture
    Applied radiation and isotopes, February 2015, Vol.96, pp.1-5 [Revue évaluée par les pairs]

    • Plusieurs versions

    Alpha particle induced DNA damage and repair in normal cultured thyrocytes of different proliferation status

    Lyckesvärd, Madeleine Nordén, Delle, Ulla, Kahu, Helena, Lindegren, Sture, Jensen, Holger, Bäck, Tom, Swanpalmer, John, Elmroth, Kecke
    Mutation research, July 2014, Vol.765, pp.48-56 [Revue évaluée par les pairs]

    • Plusieurs versions

    Comparison of therapeutic efficacy and biodistribution of 213Bi- and 211At-labeled monoclonal antibody MX35 in an ovarian cancer model

    Gustafsson, Anna M.E, Bäck, Tom, Elgqvist, Jörgen, Jacobsson, Lars, Hultborn, Ragnar, Albertsson, Per, Morgenstern, Alfred, Bruchertseifer, Frank, Jensen, Holger, Lindegren, Sture
    Nuclear medicine and biology, 2012, Vol.39(1), pp.15-22 [Revue évaluée par les pairs]

    • Plusieurs versions

    Therapeutic Efficacy of Astatine-211–Labeled Trastuzumab on Radioresistant SKOV-3 Tumors in Nude Mice

    Palm, Stig, Bäck, Tom, Claesson, Ingela, Danielsson, Anna, Elgqvist, Jörgen, Frost, Sofia, Hultborn, Ragnar, Jensen, Holger, Lindegren, Sture, Jacobsson, Lars
    International journal of radiation oncology, biology, physics, 2007, Vol.69(2), pp.572-579 [Revue évaluée par les pairs]

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    Administered activity and metastatic cure probability during radioimmunotherapy of ovarian cancer in nude mice with 211At-MX35 F(ab′) 2

    Elgqvist, Jörgen, Andersson, Håkan, Bernhardt, Peter, Bäck, Tom, Claesson, Ingela, Hultborn, Ragnar, Jensen, Holger, Johansson, Bengt R, Lindegren, Sture, Olsson, Marita, Palm, Stig, Warnhammar, Elisabet, Jacobsson, Lars
    International journal of radiation oncology, biology, physics, 2006, Vol.66(4), pp.1228-1237 [Revue évaluée par les pairs]
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    Titre: Administered activity and metastatic cure probability during radioimmunotherapy of ovarian cancer in nude mice with 211At-MX35 F(ab′) 2
    Auteur: Elgqvist, Jörgen; Andersson, Håkan; Bernhardt, Peter; Bäck, Tom; Claesson, Ingela; Hultborn, Ragnar; Jensen, Holger; Johansson, Bengt R; Lindegren, Sture; Olsson, Marita; Palm, Stig; Warnhammar, Elisabet; Jacobsson, Lars
    Sujet: Ovarian Cancer ; Radioimmunotherapy ; Dosimetry ; Mx35 ; Astatine ; Ovarian Cancer ; Radioimmunotherapy ; Dosimetry ; Mx35 ; Astatine ; Medicine
    Description: Purpose: To elucidate the therapeutic efficacy of α-radioimmunotherapy of ovarian cancer in mice. This study: (i) estimated the minimum required activity (MRA), giving a reasonable high therapeutic efficacy; and (ii) calculated the specific energy to tumor cell nuclei and the metastatic cure probability (MCP) using various assumptions regarding monoclonal-antibody (mAb) distribution in measured tumors. The study was performed using the α-particle emitter Astatine-211 ( 211At) labeled to the mAb MX35 F(ab′) 2. Methods and Materials: Animals were inoculated intraperitoneally with ∼1 × 10 7 cells of the cell line NIH:OVCAR-3. Four weeks later animals were treated with 25, 50, 100, or 200 kBq 211At-MX35 F(ab′) 2 ( n = 74). Another group of animals was treated with a nonspecific mAb: 100 kBq 211At-Rituximab F(ab′) 2 ( n = 18). Eight weeks after treatment the animals were sacrificed and presence of macro- and microscopic tumors...
    Fait partie de: International journal of radiation oncology, biology, physics, 2006, Vol.66(4), pp.1228-1237
    Identifiant: 0360-3016 (ISSN); 1879-355X (E-ISSN); 10.1016/j.ijrobp.2006.07.003 (DOI)

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    Astatine-211: The Chemistry Infrastructure

    Lindegren, Sture, Bäck, Tom, Palm, Stig, Jensen, Holger, Albertsson, Per, Aneheim, Emma
    Journal of medical imaging and radiation sciences, December 2019, Vol.50(4), pp.S94-S94 [Revue évaluée par les pairs]
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    Titre: Astatine-211: The Chemistry Infrastructure
    Auteur: Lindegren, Sture; Bäck, Tom; Palm, Stig; Jensen, Holger; Albertsson, Per; Aneheim, Emma
    Sujet: Medicine
    Fait partie de: Journal of medical imaging and radiation sciences, December 2019, Vol.50(4), pp.S94-S94
    Identifiant: 1939-8654 (ISSN); 1876-7982 (E-ISSN); 10.1016/j.jmir.2019.11.081 (DOI)

    • Plusieurs versions

    Quantified Cell Binding of Astatinated Immunoconjugates on Ovarian Cancer Cell Spheroids by Alpha Camera Imaging

    Back, Tom, Verhoeven, Marjolein, Aneheim, Emma, Albertsson, Per, Palm, Stig, Lindegren, Sture, Jensen, Holger
    Journal of medical imaging and radiation sciences, March 2019, Vol.50(1), pp.S36-S37 [Revue évaluée par les pairs]
    ScienceDirect Journals (Elsevier)
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    Astatine-211: The Chemistry Infrastructure

    Lindegren, Sture, Bäck, Tom, Palm, Stig, Jensen, Holger, Albertsson, Per, Aneheim, Emma
    Journal of medical imaging and radiation sciences, March 2019, Vol.50(1), pp.S24-S24 [Revue évaluée par les pairs]
    ScienceDirect Journals (Elsevier)