The scientist as consultant : building new career opportunities / Carl J. Sindermann and Thomas K. Sawyer
Auteur:Sindermann, Carl J Contributeur:Sawyer, Thomas K Editeur:
New York : Plenum trade
341 p. : ill.
Sujet RERO:carrière (profession) - gestion
- Scientifiques Note:
Bibliogr. p. 303-305. Index
0306456370 (ISBN); http://catalogue.bnf.fr/ark:/12148/cb37514553b (URN) No RERO:
Titre: Metagonimoides oregonensis Price, 1931 from a Georgia Raccoon with a Note on Sellacotyle mustelae Wallace, 1935 Auteur:Sawyer, Thomas K. Sujet:Biology ; Zoology; Fait partie de:
The Journal of Parasitology, 1 February 1958, Vol.44(1), pp.63-63
00223395 (ISSN); 19372345 (E-ISSN); 10.2307/3274830 (DOI)
Distribution and possible interrelationships of pathogenic and nonpathogenic Acanthamoeba from aquatic environments
Daggett, Pierre, Sawyer, Thomas, Nerad, Thomas
Microbial Ecology, 1982, Vol.8(4), pp.371-386
[Revue évaluée par les pairs]
Titre: A New Strain of Paratetramitus jugosus from Laguna Figueroa, Baja California, Mexico Auteur:Read, Laurie K.; Margulis, Lynn; Stolz, John; Obar, Robert; Sawyer, Thomas K. Sujet:Medicine ; Biology; Description:
A euryhalic, moderately temperature tolerant, fast growing strain of the amoebomastigote Paratetramitus jugosus was isolated from the North Pond flat laminated microbial mat at Laguna Figueroa, Baja California del Norte, Mexico. The morphology was studied with phase contrast, differential interference contrast, scanning, and transmission electron microscopy. On the basis of its life cycle characteristics, growth rate, salt and heat tolerance, fluorescence excitation and emission spectra, and isozymes, the organism was determined to be a new strain, P. jugosus baja californiensis. This new strain, unlike the type specimen (ATCC 30703), grows vigorously on half strength sea water and slowly at 0.51 M (nearly 3 per cent) sodium chloride. It tolerates the hypersaline conditions of the evaporite flat that prevail when the North Pond mats are dominated by Microcoleus and other bacteria, growing well during periods of influx of fresh water. Its cysts survive complete dryness of the sediment for at least three years. The microbial mats in which this Paratetramitus jugosus has been found are thought to have Archean analogues over 3 billion years old. The discovery of resistant abundant small eukaryotes within a setting dominated by bacteria may be important for the interpretation of the Proterozoic microbial fossil record.
Fait partie de:
Biological Bulletin, 1 August 1983, Vol.165(1), pp.241-264
00063185 (ISSN); 10.2307/1541367 (DOI)
Titre: The basis for variation in susceptibility to poliovirus in HeLa cells Auteur:Darnell, James E; Sawyer, Thomas K Sujet:Biology Description:
Investigation of HeLa cells which differ in their relative susceptibility to poliovirus has indicated that the “resistant” and “sensitive” cells adsorb virus with the same efficiency and are penetrated equally well by that virus which is destined to initiate infection. However, since the “resistant” cell is equally susceptible to infection by poliovirus ribonucleic acid (RNA), the basis for resistance appears to be that this cell is relatively inefficient in effecting the release of poliovirus RNA from its protein coat. Whether this inefficiency resides in a step in infection that takes place at the cell surface or at some intracellular site remains unresolved.
Fait partie de:
Virology, 1960, Vol.11(4), pp.665-675
0042-6822 (ISSN); 1096-0341 (E-ISSN); 10.1016/0042-6822(60)90113-6 (DOI)
Titre: The In vitro Development of Microfilariae of the Dog Heartworm Dirofilaria immitis to the "Sausage-Form" Auteur:Sawyer, Thomas K.; Weinstein, Paul P. Sujet:Biology ; Zoology; Description:
The microfilariae of Dirofilaria immitis were cultured to the late first-stage (sausage-form) at 27 C and at room temperature. Development was obtained by incubating heparinized blood containing microfilariae derived from three naturally infected and three experimentally infected dogs. Similarly, development occurred when the organisms were isolated from dog blood and incubated in human and rabbit blood and in medium consisting of dog blood cells suspended in Locke's saline. Survival for several weeks without development occurred in dog plasma and horse serum. In medium NCTC 109 the yield of developing parasites per culture varied with differences in serum concentration, the use of heated and unheated serum, and with different serum pools. Small numbers of white blood cells present in cultures containing medium 109 were subsequently eliminated and comparable development was obtained in cell-free media.
Fait partie de:
The Journal of Parasitology, 1 April 1963, Vol.49(2), pp.218-224
00223395 (ISSN); 19372345 (E-ISSN); 10.2307/3275987 (DOI)
Titre: Studies on the Microfilariae of the Dog Heartworm Dirofilaria immitis: Separation of Parasites from Whole Blood Auteur:Sawyer, Thomas K.; Weinstein, Paul P. Sujet:Biology ; Zoology; Description:
A technique employing saponin and enzymes (streptolysin O, trypsin) for the lysis of dog blood cells is described which fulfills several objectives for the development of in vitro culture methods with the microfilariae of D. immitis, i.e., the isolation of large numbers of viable parasites in a relatively short period of time, and the obtainment of cell-free microfilarial suspensions. Pronase and collagenase were as effective as streptolysin for yielding cell-free inocula, and under all conditions 80 to 95% of the microfilariae were routinely recovered. The viability of isolated microfilariae was assessed by noting changes in motility, the formation of vacuoles, and differences in survival or growth to the "sausage-form" in culture.
Fait partie de:
The Journal of Parasitology, 1 February 1963, Vol.49(1), pp.39-45
00223395 (ISSN); 19372345 (E-ISSN); 10.2307/3275668 (DOI)
Titre: Variation in plaque-forming ability among parental and clonal strains of HeLa cells Auteur:Darnell, James E; Sawyer, Thomas K Sujet:Biology Description:
Clonal strains of HeLa cells have been isolated which vary with respect to plaque-forming ability with poliovirus over a tenfold range.This phenomenon appears to be mediated through a heritable cellular difference and is not due to a host range virus variation.The differences in susceptibility are unexplained but are not due to the quantity of virus adsorbed, even though differences in adsorption rate were detected.
Fait partie de:
Virology, 1959, Vol.8(2), pp.223-229
0042-6822 (ISSN); 1096-0341 (E-ISSN); 10.1016/0042-6822(59)90006-6 (DOI)