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    • Article
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    Aging, an issue of the XXI(st) century

    Lagrue, Gilbert, Ménard, Joël
    Medecine sciences : M/S, March 2012, Vol.28(3), pp.235-6 [Revue évaluée par les pairs]
    MEDLINE/PubMed (U.S. National Library of Medicine)
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    Titre: Aging, an issue of the XXI(st) century
    Auteur: Lagrue, Gilbert; Ménard, Joël
    Sujet: Aging
    Fait partie de: Medecine sciences : M/S, March 2012, Vol.28(3), pp.235-6
    Identifiant: 0767-0974 (ISSN); 22480638 Version (PMID); 10.1051/medsci/2012283002 (DOI)

    • Article
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    Maladies d'Alzheimer : monographie

    Ménard, Joël
    In: Revue du praticien. - Paris. - T. 61(2011), no 7, p. 912-955
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    Titre: Maladies d'Alzheimer : monographie / [cons. scientifique] Pr Joël Menard
    Auteur: Ménard, Joël
    Publication en relation: In: Revue du praticien. - Paris. - T. 61(2011), no 7, p. 912-955
    Document hôte: Revue du praticien : journal d'enseignement post-universitaire
    Classification: cdu-vshevs 616.892
    No RERO: R008932969
    Permalien:
    http://data.rero.ch/01-R008932969/html?view=VS_V1

    • Article
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    Keys to the success of the CARMAT project?

    Ménard, Joël
    Medecine sciences : M/S, February 2014, Vol.30(2), pp.204-5 [Revue évaluée par les pairs]
    MEDLINE/PubMed (U.S. National Library of Medicine)
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    Titre: Keys to the success of the CARMAT project?
    Auteur: Ménard, Joël
    Sujet: Heart, Artificial
    Fait partie de: Medecine sciences : M/S, February 2014, Vol.30(2), pp.204-5
    Identifiant: 0767-0974 (ISSN); 24572121 Version (PMID); 10.1051/medsci/20143002020 (DOI)

    • Plusieurs versions

    Primary Cardiovascular Disease Risk Factors Predicted by Poor Working Conditions in the GAZEL Cohort

    Meneton, Pierre, Lemogne, Cédric, Herquelot, Eléonore, Bonenfant, Sébastien, Czernichow, Sébastien, Ménard, Joël, Goldberg, Marcel, Zins, Marie
    American Journal of Epidemiology, 2017, Vol. 186(7), pp.815-823 [Revue évaluée par les pairs]

    • Article
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    Plasma Angiotensins, Renin, and Blood Pressure During Acute Renin Inhibition by CGP 38 560A in Hypertensive Patients

    Jeunemaître, Xavier
    Ménard, Joël, Nussberger, Jurg, Guyene, Tam T, Brunner, Hans R, Corvol, Pierre
    American Journal of Hypertension. - 1989/2/11_Pt_1/819-827
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    Titre: Plasma Angiotensins, Renin, and Blood Pressure During Acute Renin Inhibition by CGP 38 560A in Hypertensive Patients
    Auteur: Jeunemaître, Xavier
    Contributeur: Ménard, Joël; Nussberger, Jurg; Guyene, Tam T; Brunner, Hans R; Corvol, Pierre
    Sujet: Original Contributions - Renin inhibition - plasma renin activity - plasma angiotensins - blood pressure - converting enzyme inhibition - active renin
    Description: The new renin inhibitor CGP 38560A has been shown to block angiotensin (ANG) production in healthy volunteers. In order to determine its potential antihypertensive effect, the compound was administered in a 30-min infusion, in 12 hypertensive patients (mean blood pressure (BP): 112.8 ± 3.5 mm Hg). These patients were selected for their sensitivity to Captopril: a single oral dose of 50 mg Captopril lowered their mean BP by 8.8 ± 2.2 mm Hg after 30 min and by 15.3 ± 1.5 mm Hg after 90 min. At the end of the renin inhibitor infusion, mean blood pressure decreased by 5.7 ± 2.2 mm Hg in the six patients infused with the dose of 0.125 mg/kg and by 6.0 ± 1.8 mm Hg in the six patients infused with 0.250 mg/kg. The fall in blood pressure was correlated to the initial plasma renin activity (PRA) (r = 0.61, P < .05). A dose-dependent effect was observed on plasma ANG I which fell by 74% with 0.125 mg/kg and by 94% with 0.250 mg/kg. Identical falls were found for plasma ANG II (72% and 94%, respectively) and ANG I and ANG II were well correlated (r = 0.91, P < .001). The fall in BP was correlated to the fall in plasma ANG I (r = 0.77, P < .01). The time-course of the BP changes was parallel to the changes in plasma angiotensins, as were the slightly delayed rise and fall in active renin measured by a direct immunoradiometric assay. When measured by the conventional ANG I radioimmunoassay, PRA values indicated a long-lasting inhibition. The arte- factual nature of the latter result is demonstrated by the different results obtained with an ANG I antibody-trapping radioimmunoassay, which followed more closely plasma ANG I levels. Am J Hypertens 1989; 2:819-827
    Publication en relation: American Journal of Hypertension. - 1989/2/11_Pt_1/819-827
    Document hôte: American Journal of Hypertension
    Identifiant: 10.1093/ajh/2.11.819 (DOI)

    • Film
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    Alzheimer, un nouveau regard

    Ménard, Joël, Delarue, Jean-Luc
    [France] : Réservoir Prod [prod.]
    2008
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    Titre: Alzheimer, un nouveau regard / présentation: Jean-Luc Delarue ; avec Joël Ménard ... [et al.]
    Auteur: Ménard, Joël; Delarue, Jean-Luc
    Editeur: [France] : Réservoir Prod [prod.]
    Date: 2008
    Collation: 1 DVD-vidéo (149 min.)
    Description: "La maladie Alzheimer progresse aussi vite que la population vieillit. 860'000 personnes sont touchées aujourd'hui en France, 225'000 nouveaux cas sont détectés chaque année. Les projections avancent les chiffres d'1 million de personnes atteintes de la maladie d'ici 12 ans, en 2020, et de plus de 2 millions de personnes en 2040. Il est urgent de changer le regard de chacun sur la maladie."
    Note: Diffusé le 13 février 2008 sur France2
    Classification: vs-hevs DVD-040
    No RERO: R004670328
    Permalien:
    http://data.rero.ch/01-R004670328/html?view=VS_V1

    • Article
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    Renal Proliferative and Phenotypic Changes in Rats With Two-Kidney, One-Clip Goldblatt Hypertension

    Eng, Eudora
    Veniant, Murielle, Floege, Jürgen, Fingerle, Jürgen, Alpers, Charles E, Menard, Joel, Clozel, Jean-Paul, Johnson, Richard J
    American Journal of Hypertension. - 1994/7/2/177-185
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    Titre: Renal Proliferative and Phenotypic Changes in Rats With Two-Kidney, One-Clip Goldblatt Hypertension
    Auteur: Eng, Eudora
    Contributeur: Veniant, Murielle; Floege, Jürgen; Fingerle, Jürgen; Alpers, Charles E; Menard, Joel; Clozel, Jean-Paul; Johnson, Richard J
    Sujet: Original Contributions - Angiotensin II - Goldblatt hypertension - rat - kidney
    Description: Angiotensin II (All) is a vasoconstrictive peptide with hypertrophic and mitogenic effects on many cell types. Previous studies have shown that in vivo administration of All in rats results in proliferation of, and phenotypic changes in, many renal cell populations, but in doses also causing hypertension. Thus, it was not possible to differentiate nonhemodynamic from hypertensive effects of All. Therefore, we studied rats with renin-dependent, All-mediated hypertension (the two-kidney, oneclip Goldblatt model; mean systolic blood pressure 238 ± 48 ν 140 ± 6 mm Hg in sham-operated controls). The undipped kidneys, which were exposed to high blood pressure, developed significant glomerular and tubulointerstitial injury, tubulointerstitial cell proliferation, dense focal interstitial monocyte-macrophage influx, increased deposition of types I and IV collagen, as well as increased cellular expression of desmin and actin, in tubulointerstitial areas when examined at 11 weeks. In contrast, clipped kidneys, protected from hypertension but with high local renin expression, had minimal abnormalities. These studies suggest that in this model increased renin, and presumably All, does not mediate significant proliferative or phenotypic changes in the kidney in the absence of hypertension at 11 weeks. Am J Hypertens 1994;7:177-185
    Publication en relation: American Journal of Hypertension. - 1994/7/2/177-185
    Document hôte: American Journal of Hypertension
    Identifiant: 10.1093/ajh/7.2.177 (DOI)

    • Livre
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    E-santé en perspective

    Degoulet, Patrice
    Fieschi, Marius, Ménard, Joël
    Paris : Lavoisier
    2017
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    Titre: E-santé en perspective / Patrice Degoulet, Marius Fieschi, Joël Ménard
    Auteur: Degoulet, Patrice
    Contributeur: Fieschi, Marius; Ménard, Joël
    Editeur: Paris : Lavoisier
    Date: 2017
    Collation: 211 S.
    Sujet RERO: Télémédecine
    Sujet RERO - forme: [Études diverses]
    Classification: cdu-vshevl 614
    Identifiant: 9782867280146 (ISBN); http://catalogue.bnf.fr/ark:/12148/cb45335920m (URN)
    No RERO: R008858844
    Permalien:
    http://data.rero.ch/01-R008858844/html?view=VS_V1

    • Plusieurs versions

    Inhibitor of Fatty Acid Amide Hydrolase — Learning from Tragic Failures

    Funck-Brentano, Christian, Ménard, Joël
    The New England journal of medicine, 26 January 2017, Vol.376(4), pp.292-3 [Revue évaluée par les pairs]

    • Plusieurs versions

    A Global View of the Relationships between the Main Behavioural and Clinical Cardiovascular Risk Factors in the GAZEL Prospective Cohort

    Meneton, Pierre, Lemogne, Cédric, Herquelot, Eléonore, Bonenfant, Sébastien, Larson, Martin G, Vasan, Ramachandran S, Ménard, Joël, Goldberg, Marcel, Zins, Marie
    PLoS ONE, 06 September 2016, Vol.11(9), p.e0162386 [Revue évaluée par les pairs]